{"schemaVersion":"cwiki-fiche-2.0","identifiers":{"inchiKey":"CDOSHBSSFJOMGT-UHFFFAOYSA-N","prefName":"Linalol","symbol":"Linalol","iupacName":"3,7-diméthylocta-1,6-dién-3-ol","aliases":["linalool","β-linalol","β-linalool","alcool linalylique","3,7-diméthylocta-1,6-dién-3-ol"],"cas":"78-70-6","pubchemCid":"6549","chebiId":"CHEBI:17580","smiles":"CC(=CCCC(C)(C=C)O)C","molecularFormula":"C10H18O","molecularWeight":154.25,"xrefs":{"pubchem":"https://pubchem.ncbi.nlm.nih.gov/compound/6549","chebi":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:CHEBI:17580"}},"classification":{"family":"terpene","familyLabel":"Terpeno","origin":"plant","originLabel":"Plante","subgroup":"monoterpene","subgroupLabel":"Monoterpeno","originCode":"E","originCodeLabel":"Biosíntesis enzimática en la planta","originDebated":false,"chemicalClass":"Monoterpène acyclique (alcool tertiaire, sans le squelette des cannabinoïdes)","sideChain":null,"form":null,"parent":null,"pharmacologicalClass":null,"naturalTrace":null,"structuralClassFr":null},"originSynthesis":{"heading":"Vía biosintética","summaryFr":"Como los demás monoterpenos, el linalol deriva del pirofosfato de geranilo, precursor de diez carbonos que las terpeno sintasas convierten en monoterpenos y que también interviene en la biosíntesis de los cannabinoides (Booth 2017). En los tricomas glandulares del cannabis, dos enzimas caracterizadas funcionalmente, CsTPS18VF y CsTPS19BL, son sintasas de nerolidol y linalol (Zager 2019). El contenido depende de la variedad: el cáñamo « Finola » contiene pocos alcoholes monoterpénicos como el linalol, aunque son comunes en otras variedades (Booth 2017).","originNote":"Alcohol monoterpénico presente en los aceites esenciales de numerosas plantas aromáticas. Representaba del 23,8 al 33,0 % del aceite esencial de lavanda (Lavandula angustifolia) en 20 lotes auténticos, frente a un intervalo del 20,0 al 45,0 % fijado por la Farmacopea Europea (Capetti 2021), y alrededor del 70 % del aceite esencial de frutos de cilantro (Burdock 2009). Figura entre los terpenoides más comunes del cannabis (Santiago 2019), sin estar entre los tres más abundantes de media en las muestras comerciales estadounidenses, que son el mirceno, el β-cariofileno y el limoneno (Smith 2022). El cáñamo lo produce por sí mismo gracias a terpeno sintasas de sus tricomas (Zager 2019).","discovered":""},"pharmacology":{"summaryFr":"El linalol es un terpeno y no un cannabinoide: alcohol monoterpénico acíclico de diez carbonos, no tiene ni el esqueleto de los fitocannabinoides ni una afinidad establecida por sus receptores. Existe en forma de dos enantiómeros, el (R)-(−)-linalol, aislado del aceite de lavanda, y el (S)-(+)-linalol, aislado del aceite de cilantro (Sugawara 2000); en 20 aceites de lavanda auténticos, la forma (R) representaba el 93,8 % del linalol (Capetti 2021). Su acción sobre los receptores cannabinoides sigue en discusión. En células que expresan el CB1 o el CB2 humano, no produjo ningún efecto hasta 100 µM, solo o asociado al Δ9-THC (Santiago 2019); el estudio de Finlay et al. (2020), citado a menudo junto a él, no probó el linalol. LaVigne et al. (2021) describieron en cambio una activación del CB1 sensible al rimonabant, a concentraciones superiores a 10 µM y de hasta 500 µM según el terpeno, sin unión medible al sitio ortostérico; en el ratón, 200 mg/kg por vía intraperitoneal produjeron hipotermia, catalepsia e hipolocomoción, así como una débil antinocicepción bloqueada por el rimonabant. Otras dianas solo aparecen a concentraciones milimolares: potenciación de los receptores GABA-A (Milanos 2017), inhibición no competitiva de la unión al receptor NMDA (Brum 2001). En el ratón, el olor del linalol produjo un efecto de tipo ansiolítico sin alteración motora, ausente en los animales vueltos anósmicos y abolido por el flumazenil (Harada 2018); inhalado durante una hora al 1 o al 3 %, prolongó el sueño inducido por el pentobarbital sin alterar la coordinación motora (Linck 2009). En el ser humano, los datos farmacocinéticos se limitan a unas pocas mediciones, entre ellas un pico plasmático de 121 ng/ml 19 minutos después de un masaje con aceite de lavanda en un voluntario (EMA 2012). En el aire, el linalol se oxida en hidroperóxidos alergénicos: probado al 6,0 % en 2 900 pacientes de seis países, el linalol oxidado dio un 6,9 % de reacciones positivas (Bråred Christensson 2012). En los Estados Unidos, figura entre las sustancias aromatizantes sintéticas reconocidas como seguras (21 CFR 182.60).","receptorSummaryFr":"El linalol no es un ligando cannabinoide establecido, y los dos estudios que lo probaron en estos receptores discrepan. En células AtT20 que expresan el CB1 o el CB2 humano, el linalol racémico, de 1 nM a 100 µM, no modificó ni el potencial de membrana ni la respuesta al CP55,940 o al Δ9-THC (Santiago 2019). En células CHO que expresan el CB1 humano, en cambio, activó la ERK de forma sensible al rimonabant e inhibió parcialmente la producción de AMPc, pero solo a altas concentraciones micromolares, sin desplazar de forma medible el [3H]CP55,940 ni reclutar la β-arrestina 2; los autores no descartan un mecanismo indirecto, a través de la membrana o del 2-AG (LaVigne 2021). Fuera del sistema cannabinoide, a 2 mM potencia la corriente de receptores GABA-A α1β2γ2 recombinantes (Milanos 2017), inhibe de forma no competitiva la unión del [3H]MK801 al complejo del receptor NMDA (CI50 = 2,97 mM) sin modificar la del [3H]muscimol (Brum 2001), y bloquea la corriente de sodio dependiente de voltaje de neuronas disociadas de ganglios raquídeos (Leal-Cardoso 2010).","binding":[{"target":"CB1","efficacy":"unknown","measure":null,"valueNm":null,"species":"humano","assay":"potencial de membrana (FLIPR), células AtT20 que expresan el CB1 humano; linalol racémico de 1 nM a 100 µM","source":{"label":"Santiago et al. 2019, Cannabis Cannabinoid Res","pmid":"31559333","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/31559333/"},"strength":null,"reported":"Ninguna hiperpolarización propia y ninguna modificación de la respuesta al CP55,940 (1 µM) ni al Δ9-THC (Santiago 2019)","confidence":"low"},{"target":"CB2","efficacy":"unknown","measure":null,"valueNm":null,"species":"humano","assay":"potencial de membrana (FLIPR), células AtT20 que expresan el CB2 humano; linalol racémico de 1 nM a 100 µM","source":{"label":"Santiago et al. 2019, Cannabis Cannabinoid Res","pmid":"31559333","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/31559333/"},"strength":null,"reported":"Ninguna hiperpolarización propia y ninguna modificación de la respuesta al CP55,940 (1 µM) ni al Δ9-THC (Santiago 2019)","confidence":"low"},{"target":"CB1","efficacy":"full_agonist","measure":null,"valueNm":null,"species":"humano","assay":"fosforilación de la ERK bloqueada por el rimonabant e inhibición parcial del AMPc estimulado por la forskolina, células CHO que expresan el CB1 humano","source":{"label":"LaVigne et al. 2021, Sci Rep","pmid":"33859287","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/33859287/"},"strength":null,"reported":"Activación de baja potencia, a concentraciones micromolares altas (500 µM en el ensayo con rimonabant), sin curva ajustable; ningún desplazamiento medible del [3H]CP55,940 ni reclutamiento de la β-arrestina 2 (LaVigne 2021)","confidence":"low"},{"target":"CB2","efficacy":"unknown","measure":null,"valueNm":null,"species":"humano","assay":"fosforilación de la ERK, células CHO que expresan el CB2 humano","source":{"label":"LaVigne et al. 2021, Sci Rep","pmid":"33859287","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/33859287/"},"strength":null,"reported":"Fosforilación de la ERK notificada en una figura suplementaria, sin prueba con antagonista ni caracterización farmacológica (LaVigne 2021)","confidence":"low"},{"target":"GABA-A","efficacy":"positive_allosteric_modulator","measure":null,"valueNm":null,"species":null,"assay":"corriente de cloruro inducida por 10 µM de GABA, receptor α1β2γ2 expresado en células HEK293 (célula entera)","source":{"label":"Milanos et al. 2017, Front Chem","pmid":"28680877","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/28680877/"},"strength":null,"reported":"Corriente elevada al 160 ± 14 % del control por 2 mM de linalol (Milanos 2017)","confidence":"low"},{"target":"GABA-A","efficacy":"unknown","measure":null,"valueNm":null,"species":"ratón","assay":"unión del [3H]muscimol (sitio del GABA), membranas corticales","source":{"label":"Brum, Elisabetsky & Souza 2001, Phytother Res","pmid":"11507735","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/11507735/"},"strength":null,"reported":"Ningún efecto sobre la unión del [3H]muscimol (Brum 2001)","confidence":"low"},{"target":"NMDA","efficacy":"binding_only","measure":"IC50","valueNm":2970000,"species":"ratón","assay":"inhibición no competitiva de la unión del [3H]MK801, membranas corticales","source":{"label":"Brum, Elisabetsky & Souza 2001, Phytother Res","pmid":"11507735","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/11507735/"},"strength":4,"reported":null,"confidence":"high"}],"references":[{"label":"Santiago et al. 2019, Cannabis Cannabinoid Res: absence of entourage, terpenoids commonly found in Cannabis sativa do not modulate Δ9-THC at human CB1 and CB2 receptors (linalol incluido)","pmid":"31559333","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6757242/"},{"label":"LaVigne et al. 2021, Sci Rep: terpenos cannabimiméticos del cannabis, activación del CB1 a concentraciones altas","pmid":"33859287","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8050080/"},{"label":"Finlay et al. 2020, Front Pharmacol: terpenoids from cannabis do not mediate an entourage effect by acting at cannabinoid receptors (linalol no ensayado)","pmid":"32269529","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7109307/"},{"label":"Zager et al. 2019, Plant Physiol: gene networks underlying cannabinoid and terpenoid accumulation in cannabis, sintasas del nerolidol y del linalol","pmid":"31138625","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/31138625/"},{"label":"Booth et al. 2017, PLoS One: terpeno sintasas de Cannabis sativa","pmid":"28355238","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5371325/"},{"label":"Harada et al. 2018, Front Behav Neurosci: linalool odor-induced anxiolytic effects in mice","pmid":"30405369","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6206409/"},{"label":"Linck et al. 2009, Phytomedicine: inhaled linalool-induced sedation in mice","pmid":"18824339","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/18824339/"},{"label":"Milanos et al. 2017, Front Chem: metabolic products of linalool and modulation of GABAA receptors","pmid":"28680877","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5478857/"},{"label":"Brum, Elisabetsky & Souza 2001, Phytother Res: effects of linalool on [3H]MK801 and [3H]muscimol binding in mouse cortical membranes","pmid":"11507735","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/11507735/"},{"label":"Leal-Cardoso et al. 2010, Eur J Pharmacol: linalool blocks excitability in peripheral nerves and voltage-dependent Na+ current","pmid":"20655301","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/20655301/"},{"label":"Sugawara et al. 2000, Chem Senses: odor distinctiveness between enantiomers of linalool","pmid":"10667997","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/10667997/"},{"label":"Capetti et al. 2021, Molecules: adulteration of essential oils, lavender case study (linalool and enantiomeric composition)","pmid":"34577081","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8471154/"},{"label":"Burdock & Carabin 2009, Food Chem Toxicol: safety assessment of coriander essential oil (linalol, alrededor del 70 %)","pmid":"19032971","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/19032971/"},{"label":"Smith et al. 2022, PLoS One: the phytochemical diversity of commercial cannabis in the United States","pmid":"35588111","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9119530/"},{"label":"Chadha & Madyastha 1984, Xenobiotica: metabolism of geraniol and linalool in the rat","pmid":"6475100","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/6475100/"},{"label":"Meesters, Duisken & Hollender 2007, Xenobiotica: cytochrome P450-mediated oxidative metabolism of linalool","pmid":"17614007","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/17614007/"},{"label":"Debong et al. 2024, Mol Nutr Food Res: linalool, 1,8-cineole and eugenol transfer from a curry dish into human urine","pmid":"37953385","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/37953385/"},{"label":"Doroshyenko et al. 2013, Drug Metab Dispos: Silexan (aceite de lavanda oral) y citocromos P450 en voluntarios sanos","pmid":"23401474","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/23401474/"},{"label":"Heuberger, Redhammer & Buchbauer 2004, Neuropsychopharmacology: transdermal absorption of (-)-linalool in humans","pmid":"15238993","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/15238993/"},{"label":"Sköld et al. 2004, Chem Res Toxicol: contact allergens formed on air exposure of linalool","pmid":"15606147","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/15606147/"},{"label":"Christensson et al. 2010, Contact Dermatitis: linalool, a significant contact sensitizer after air exposure","pmid":"20136877","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/20136877/"},{"label":"Bråred Christensson et al. 2012, Contact Dermatitis: air-oxidized linalool, a frequent cause of fragrance contact allergy","pmid":"22906042","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/22906042/"},{"label":"Fischedick et al. 2010, Phytochemistry: metabolic fingerprinting of Cannabis sativa, cannabinoids and terpenoids (GC-FID validada)","pmid":"21040939","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/21040939/"},{"label":"EMA/HMPC/143183/2010, informe de evaluación sobre Lavandula angustifolia (27 de marzo de 2012): farmacocinética y toxicología del linalol","pmid":null,"doi":null,"url":"https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-lavandula-angustifolia-miller-aetheroleum-and-lavandula-angustifolia-miller-flos_en.pdf"},{"label":"Reglamento de Ejecución (UE) n.º 872/2012: lista de la Unión de sustancias aromatizantes, FL 02.013 linalol","pmid":null,"doi":null,"url":"https://eur-lex.europa.eu/legal-content/FR/TXT/?uri=CELEX:32012R0872"},{"label":"Reglamento (CE) n.º 1223/2009 sobre los productos cosméticos, anexo III, entrada 84 (linalol)","pmid":null,"doi":null,"url":"https://eur-lex.europa.eu/legal-content/FR/TXT/?uri=CELEX:32009R1223"},{"label":"Reglamento (UE) 2017/776: clasificación armonizada CLP del linalol, Skin Sens. 1B (índice 603-235-00-2)","pmid":null,"doi":null,"url":"https://eur-lex.europa.eu/legal-content/FR/TXT/?uri=CELEX:32017R0776"},{"label":"21 CFR 182.60: synthetic flavoring substances and adjuvants (linalool)","pmid":null,"doi":null,"url":"https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-182/subpart-A/section-182.60"},{"label":"JIFE, Lista Verde, 36.ª ed. 2025 (Convenio de 1971)","pmid":null,"doi":null,"url":"https://www.incb.org/incb/uploads/documents/Psychotropics/forms/greenlist/2026/2510307E.pdf"},{"label":"PubChem CID 6549, linalool","pmid":null,"doi":null,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/6549"}]},"pharmacokinetics":null,"metabolism":null,"detection":null,"subjectiveEffects":{"state":"uncharacterised","method":"https://es.phytogrammes.com/wiki/a-propos#methode-effets","axes":[],"doseRanges":null,"humanDataCharacterised":true},"indications":{"approvedMedicines":[]},"harmProfile":{"unstudiedBanner":false,"bannerTextFr":null,"toxicologyFr":null},"legal":{"scheduleStatus":"unscheduled","scheduleLabel":"No listado","frScheduleStatus":"unscheduled","tiers":[{"jurisdiction":"international","jurisdictionLabel":"International","label":null,"reference":null,"url":null,"effectiveDate":null,"lastVerified":"2026-10-20","supersededBy":null},{"jurisdiction":"eu","jurisdictionLabel":"Union européenne","label":"El linalol no figura en ninguna lista de las convenciones de las Naciones Unidas de 1961 y 1971. En la Unión Europea, está inscrito sin restricción de uso en la lista de sustancias aromatizantes autorizadas (Reglamento de Ejecución (UE) n.º 872/2012, FL 02.013). El Reglamento (CE) n.º 1223/2009 sobre los productos cosméticos obliga a mencionarlo en la lista de ingredientes por encima del 0,001 % en los productos que no se aclaran y del 0,01 % en los que se aclaran (anexo III, entrada 84). Desde el 1 de diciembre de 2018, el Reglamento CLP le atribuye, así como a sus dos enantiómeros, una clasificación armonizada de sensibilizante cutáneo de categoría 1B, H317 (Reglamento (UE) 2017/776).","reference":null,"url":null,"effectiveDate":null,"lastVerified":"2026-10-20","supersededBy":null},{"jurisdiction":"fr","jurisdictionLabel":"France","label":"No clasificado como estupefaciente en Francia: el linalol no figura en ningún anexo de la lista consolidada de estupefacientes publicada por la ANSM (actualización del 26/06/2026), que recopila el arrêté del 22 de febrero de 1990 y las decisiones de la ANSM. Como aroma e ingrediente de perfumería, depende del derecho alimentario y del derecho de los cosméticos.","reference":null,"url":null,"effectiveDate":null,"lastVerified":"2026-10-20","supersededBy":null}],"sourcesFr":"EUR-Lex, UNODC, CND, ANSM, IUPHAR/BPS, ChEBI, EUDA."},"references":[{"label":"Santiago et al. 2019, Cannabis Cannabinoid Res: absence of entourage, terpenoids commonly found in Cannabis sativa do not modulate Δ9-THC at human CB1 and CB2 receptors (linalol incluido)","pmid":"31559333","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6757242/"},{"label":"LaVigne et al. 2021, Sci Rep: terpenos cannabimiméticos del cannabis, activación del CB1 a concentraciones altas","pmid":"33859287","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8050080/"},{"label":"Finlay et al. 2020, Front Pharmacol: terpenoids from cannabis do not mediate an entourage effect by acting at cannabinoid receptors (linalol no ensayado)","pmid":"32269529","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7109307/"},{"label":"Zager et al. 2019, Plant Physiol: gene networks underlying cannabinoid and terpenoid accumulation in cannabis, sintasas del nerolidol y del linalol","pmid":"31138625","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/31138625/"},{"label":"Booth et al. 2017, PLoS One: terpeno sintasas de Cannabis sativa","pmid":"28355238","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5371325/"},{"label":"Harada et al. 2018, Front Behav Neurosci: linalool odor-induced anxiolytic effects in mice","pmid":"30405369","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6206409/"},{"label":"Linck et al. 2009, Phytomedicine: inhaled linalool-induced sedation in mice","pmid":"18824339","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/18824339/"},{"label":"Milanos et al. 2017, Front Chem: metabolic products of linalool and modulation of GABAA 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safety assessment of coriander essential oil (linalol, alrededor del 70 %)","pmid":"19032971","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/19032971/"},{"label":"Smith et al. 2022, PLoS One: the phytochemical diversity of commercial cannabis in the United States","pmid":"35588111","doi":null,"url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9119530/"},{"label":"Chadha & Madyastha 1984, Xenobiotica: metabolism of geraniol and linalool in the rat","pmid":"6475100","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/6475100/"},{"label":"Meesters, Duisken & Hollender 2007, Xenobiotica: cytochrome P450-mediated oxidative metabolism of linalool","pmid":"17614007","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/17614007/"},{"label":"Debong et al. 2024, Mol Nutr Food Res: linalool, 1,8-cineole and eugenol transfer from a curry dish into human urine","pmid":"37953385","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/37953385/"},{"label":"Doroshyenko et al. 2013, Drug Metab Dispos: Silexan (aceite de lavanda oral) y citocromos P450 en voluntarios sanos","pmid":"23401474","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/23401474/"},{"label":"Heuberger, Redhammer & Buchbauer 2004, Neuropsychopharmacology: transdermal absorption of (-)-linalool in humans","pmid":"15238993","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/15238993/"},{"label":"Sköld et al. 2004, Chem Res Toxicol: contact allergens formed on air exposure of linalool","pmid":"15606147","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/15606147/"},{"label":"Christensson et al. 2010, Contact Dermatitis: linalool, a significant contact sensitizer after air exposure","pmid":"20136877","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/20136877/"},{"label":"Bråred Christensson et al. 2012, Contact Dermatitis: air-oxidized linalool, a frequent cause of fragrance contact allergy","pmid":"22906042","doi":null,"url":"https://pubmed.ncbi.nlm.nih.gov/22906042/"},{"label":"Fischedick et al. 2010, Phytochemistry: 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armonizada CLP del linalol, Skin Sens. 1B (índice 603-235-00-2)","pmid":null,"doi":null,"url":"https://eur-lex.europa.eu/legal-content/FR/TXT/?uri=CELEX:32017R0776"},{"label":"21 CFR 182.60: synthetic flavoring substances and adjuvants (linalool)","pmid":null,"doi":null,"url":"https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-182/subpart-A/section-182.60"},{"label":"JIFE, Lista Verde, 36.ª ed. 2025 (Convenio de 1971)","pmid":null,"doi":null,"url":"https://www.incb.org/incb/uploads/documents/Psychotropics/forms/greenlist/2026/2510307E.pdf"},{"label":"PubChem CID 6549, linalool","pmid":null,"doi":null,"url":"https://pubchem.ncbi.nlm.nih.gov/compound/6549"}],"meta":{"slug":"linalol","url":"https://es.phytogrammes.com/wiki/linalol","lastVerified":"2026-10-20","dataUpdatedAt":"2026-10-27","confidence":"high","dataCompletenessPct":80,"audit":null,"wikipedia":null,"disclaimerFr":"Contenu éditorial informatif, sans valeur d'avis médical ni juridique. Sources primaires citées par fiche. Réservé aux adultes."}}